a novel method for preparation of solid lipid nanoparticles intended for drug delivery

Application of Supercritical Fluid ‎Technology for Preparation of Drug Loaded ‎Solid Lipid Nanoparticles

   Small changes in pressure or temperature, close to the critical point, lead to large changes in solubility of supercritical carbon dioxide (CO2). Environmentally friendly supercritical CO2 is the most popular and inexpensive solvent which has been used for preparation of nanodrugs and nanocarriers in drug delivery system with supercritical fluid technology. Delivery...

“Characterization of Nanoparticles Intended for Drug Delivery”

Not least because of the nano-hype, a myriad of labs focuses their research on nanoparticles. Inexplicably, a collection of lab protocols was not available until now. That way, this book fills a gap by offering a basic set of methods for pre-clinical characterization of nanomaterials provided by experienced people from the National Cancer Institute's Nanotechnology Lab. Before starting the expe...

Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery

Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics. The ability to incorporate drugs into nanoparticles offers a new prototype in drug delivery thus realizing the dual goal of both controlled release and site-specific drug delivery. Drug deliv...

Preparation and Characterization of Sildenafil Loaded Solid Lipid Nanoparticles: Drug Delivery System Suitable for Nebulization

Solid lipid nanoparticles for targeted brain drug delivery.

The present review discusses the potential use of solid lipid nanoparticles for brain drug targeting purposes. The state of the art on surfactant-coated poly(alkylcyanoacrylate) nanoparticles specifically designed for brain targeting is given by emphasizing the transfer of this technology to solid lipid matrices. The available literature on solid lipid nanoparticles and related carriers for bra...

Solid Lipid Nanoparticles of Guggul Lipid as Drug Carrier for Transdermal Drug Delivery

Diclofenac sodium loaded solid lipid nanoparticles (SLNs) were formulated using guggul lipid as major lipid component and analyzed for physical parameters, permeation profile, and anti-inflammatory activity. The SLNs were prepared using melt-emulsion sonication/low temperature-solidification method and characterized for physical parameters, in vitro drug release, and accelerated stability studi...